844698-91-5

Upstream product

• 484061-58-7 tert-butyl (2S,5S,6S)-2-benzyloxymethyl-6-[(1E,3S)-3-hydroxynon-1-enyl]-1-azaspiro[4.5]decane-1-carboxylate 
• 484061-47-4 tert-butyl (2S,5S,6S)-2-benzyloxymethyl-6-[(1E,3S/R)-3-(formyloxy)non-1-enyl]-1-azaspiro[4.5]decane-1-carboxylate 
• 484061-49-6 tert-butyl (2S,5S,6S)-2-benzyloxymethyl-6-[(1E,3S/R)-3-hydroxynon-1-enyl]-1-azaspiro[4.5]decane-1-carboxylate 
• 484061-51-0 tert-butyl (2S,5S,6S)-2-benzyloxymethyl-6-[(1E)-3-oxonon-1-enyl]-1-azaspiro[4.5]decane-1-carboxylate 
• 484061-45-2 tert-butyl (1S)-[(9E,11E)-1-benzyloxymethyl-4-oxo-9,11-octadecadienyl]carbamate 
• 152500-21-5 (S)-5-benzyloxymetyl-1-tert-butoxycarbonyl-2-pyrrolidinone 

Downstream Products

• 844698-94-8 tert-butyl (2S,5S,6R)-2-[(benzyloxy)methyl]-6-{(1S,3S)-1-hydroxy-3-[(methylsulfonyl)oxy]nonyl}-1-azaspiro[4.5]decane-1-carboxylate 
• 844698-95-9 (3S,5R,7S,7aR,11aR)-3-[(benzyloxy)methyl]-5-hexyldecahydro-1H-pyrrolo[2,1-j]quinolin-7-ol 
• 844698-97-1 (3S,5R,7aS,11aS)-3-[(benzyloxy)methyl]-5-hexyloctahydro-1H-pyrrolo[2,1-j]quinolin-7(7aH)-one 
• 844698-93-7 tert-butyl (2S,5S,6R)-2-[(benzyloxy)methyl]-6-[(1S,3S)-1,3-dihydroxynonyl]-1-azaspiro[4.5]decane-1-carboxylate 

Relevant academic research and scientific papers

Total synthesis of the tricyclic marine alkaloids (-)-lepadiformine, (+)-cylindricine C, and (-)-fasicularin via a common intermediate formed by formic acid-induced intramolecular conjugate azaspirocyclization

A very short and efficient enantioselective total synthesis of the tricyclic marine alkaloids (-)-lepadiformine (3), (+)-cylindricine C (1c), and (-)-fasicularin (4) has been developed utilizing the formyloxy 1-azaspiro[4.5]decane 5 as a common intermedia