844840-99-9Relevant academic research and scientific papers
Synthesis, characterization and nuclease activity of copper(II), nickel(II), cobalt(II) and iron(II) complexes with oxime-thiosemicarbazones
Reddy, K. Hussain,Babu, M. Surendra,Babu, P. Suresh,Dayananda
, p. 1233 - 1238 (2007/10/03)
A novel ligand viz. 1-phenyl-1,2-propanedione-2-oxime thiosemicarbazone (PPDOT) has been synthesized and characterized. Complexes of copper(II), nickel(II), cobalt(II) and iron(II) with PPDOT have been synthesized and characterized by molar conductance, magnetic moments, electronic, IR and ESR spectroscopy. Electrochemical behaviour of these complexes is investigated by cyclic voltammetric studies. The nuclease activity of these complexes has been carried out on double stranded pBR 322 plasmid DNA by using gel electrophoresis experiments in absence and in the presence of oxidant (H2O 2). Metal complexes of diacetylmonoxime thiosemicarbazone (DAMOT) are also investigated for better comparison.
