844873-53-6 Usage
Industry use
pharmaceutical industry
Type of compound
chemical compound
Derivative of
pyrrolidinecarboxylic acid
Therapeutic potential
potential therapeutic applications
Active pharmaceutical ingredient
the compound itself
Stability
tert-butyl ester group provides stability
Bioavailability
tert-butyl ester group enhances bioavailability
Medicinal properties
may have anti-inflammatory, analgesic, or other medicinal properties
Promising candidate
for drug development
Versatile chemical
for various pharmaceutical formulations
Influencing factors
cyclopentyloxy and methoxyphenyl groups can influence pharmacokinetic and pharmacodynamic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 844873-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,4,8,7 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 844873-53:
(8*8)+(7*4)+(6*4)+(5*8)+(4*7)+(3*3)+(2*5)+(1*3)=206
206 % 10 = 6
So 844873-53-6 is a valid CAS Registry Number.
844873-53-6Relevant articles and documents
Synthesis of 4-aryl-2-pyrrolidones and β-aryl-γ-amino-butyric acid (GABA) analogues by Heck arylation of 3-pyrrolines with arenediazonium tetrafluoroborates. Synthesis of (±)-rolipram on a multigram scale and chromatographic resolution by semipreparative chiral simulated moving bed chromatography
Garcia, Ariel L. L.,Carpes, Marcos J. S.,De Oca, Antonio C. B. M.,Dos Santos, Marco A. G.,Santana, Cesar C.,Correia, Carlos Roque D.
, p. 1050 - 1053 (2007/10/03)
(Chemical Equation Presented) We report herein a new, practical, and economic synthesis of the phosphodiesterase inhibitor Rolipram on a multigram scale as well as the synthesis of new 4-aryl pyrrolidones and β-aryl-γ-amino butyric acids (GABA derivatives) employing an efficient Heck-Matsuda arylation of 3-pyrroline with aryldiazonium tetrafluoroborates. Racemic Rolipram was resolved into its enantiomers using chiral simulated moving bed chromatography having the low-cost microcrystalline cellulose triacetate as a chiral stationary phase.
