84488-77-7

Basic information

• Product Name: (S)-2-hydrazino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropionic acid
• Synonyms: (S)-2-hydrazino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropionic acid;(S)-α-Hydrazino-4-hydroxy-3-methoxy-α-methylbenzenepropionic acid;(S)-α-Hydrazino-α-methyl-3-methoxy-4-hydroxybenzenepropanoic acid;3-O-Methylcarbidopa;Einecs 282-948-7
• CAS NO: 84488-77-7
• Molecular Formula: C₁₁H₁₆N₂O₄
• Molecular Weight: 240.25574
• EINECS: 282-948-7
• Mol File: 84488-77-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 486.287°C at 760 mmHg
• Flash Point: 247.897°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Heated)
• CAS DataBase Reference: (S)-2-hydrazino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-hydrazino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropionic acid(84488-77-7)
• EPA Substance Registry System: (S)-2-hydrazino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropionic acid(84488-77-7)

Safety Data

• Hazardous Substances Data: 84488-77-7(Hazardous Substances Data)

Usage

Uses

3-O-Methylcarbidopa is an impurity of Carbidopa (C175915) with potential use as therapeutic agents to treat hypertension and Parkinson''s disease.

InChI:InChI=1/C11H16N2O4/c1-11(13-12,10(15)16)6-7-3-4-8(14)9(5-7)17-2/h3-5,13-14H,6,12H2,1-2H3,(H,15,16)/t11-/m0/s1

Upstream product

• 167481-92-7 2-Hydrazino-3-(4-hydroxy-3-methoxy-phenyl)-2-methyl-propionic acid butyl ester 

Relevant articles and documents

Biocatalytic Resolution of Tertiary α-Substituted Carboxylic Acid Esters: Efficient Preparation of a Quaternary Asymmetric Carbon Center

A method for resolving a variety of tertiary α-substituted carboxylic acid esters employing a previously undescribed enzyme is reported.