84499-72-9

Basic information

• Product Name: (S)-1-(p-Tolyl)ethanaMine hydrochloride
• Synonyms: (S)-1-(p-Tolyl)ethanaMine hydrochloride;(S)-1-(4-methylphenyl)ethanamine,hydrochloride;(S)-(-)-1-(P-TOLYL)ETHYLAMINE-HCl
• CAS NO: 84499-72-9
• Molecular Formula: C₉H₁₃N*ClH
• Molecular Weight: 171.66716
• Mol File: 84499-72-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (S)-1-(p-Tolyl)ethanaMine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(p-Tolyl)ethanaMine hydrochloride(84499-72-9)
• EPA Substance Registry System: (S)-1-(p-Tolyl)ethanaMine hydrochloride(84499-72-9)

Safety Data

• Hazardous Substances Data: 84499-72-9(Hazardous Substances Data)

Usage

General Description

"(S)-1-(p-Tolyl)ethanaMine hydrochloride" is a chemical compound commonly used as a reagent in organic synthesis. It is a white crystalline powder that is soluble in water and has a molecular weight of 185.67 g/mol. (S)-1-(p-Tolyl)ethanaMine hydrochloride is often utilized in the pharmaceutical industry for the production of various drugs and medications. It is also used as a chiral auxiliary in asymmetric synthesis and as a ligand in coordination chemistry. Additionally, it has applications in the development of polymers and other organic materials. Overall, "(S)-1-(p-Tolyl)ethanaMine hydrochloride" is a versatile and important chemical compound in the field of organic chemistry.

Upstream product

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Relevant articles and documents

Synthesis method of primary amine hydrochloride

The invention discloses a synthesis method of primary amine hydrochloride. According to the synthesis method, in the presence of a gold complex, water and alkyne carry out catalytic hydrolysis to generate ketones, and then ketones and ammonium formate are catalyzed by a rhodium complex to generate primary amine. Compared with a conventional primary amine synthesis method, the synthesis method hasthe advantages that no alkali is added during the reaction process, no side product is generated, the atomic economy is good, the reaction conditions are mild, and the synthesis method has a wide prospect.

Rhodium-catalyzed asymmetric hydrogenation of unprotected NH imines assisted by a thiourea

Asymmetric hydrogenation of unprotected NH imines catalyzed by rhodium/bis(phosphine)-thiourea provided chiral amines with up to 97% yield and 95% ee. 1HNMR studies, coupled with control experiments, implied that catalytic chloride-bound intermediates were involved in the mechanism through a dual hydrogen-bonding interaction. Deuteration experiments proved that the hydrogenation proceeded through a pathway consistent with an imine.