84499-78-5 Usage
Uses
Used in Pharmaceutical Industry:
Benzenemethanamine, α-methyl-4-(trifluoromethyl)-, hydrochloride, (S)is used as a central nervous system stimulant for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Its application is based on its ability to stimulate the central nervous system, enhancing focus, attention, and reducing excessive sleepiness.
Used in Research and Development:
In the pharmaceutical research and development sector, Benzenemethanamine, α-methyl-4-(trifluoromethyl)-, hydrochloride, (S)is employed as a compound with potential therapeutic effects. Its unique structure and properties make it a valuable candidate for the development of new drugs and therapies targeting various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 84499-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,9 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84499-78:
(7*8)+(6*4)+(5*4)+(4*9)+(3*9)+(2*7)+(1*8)=185
185 % 10 = 5
So 84499-78-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3N.ClH/c1-6(13)7-2-4-8(5-3-7)9(10,11)12;/h2-6H,13H2,1H3;1H/t6-;/m0./s1
84499-78-5Relevant academic research and scientific papers
CARBAMATE DERIVATIVES AND USES THEREOF
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Paragraph 01340; 01354; 01376-01377, (2020/08/13)
The present disclosure relates to compounds of Formula (I): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.
Reversal of diastereofacial selectivity in hydride reductions of N-tert-butanesulfinyl imines
Colyer, John T.,Andersen, Neil G.,Tedrow, Jason S.,Soukup, Troy S.,Faul, Margaret M.
, p. 6859 - 6862 (2007/10/03)
A variety of N-tert-butanesulfinyl imines were reduced with NaBH 4 in THF containing 2% water to provide the corresponding secondary sulfinamides in high yield and diastereoselectivity. By using the same sulfinyl imine starting materials and changing the reductant to L-Selectride, the stereoselectivity could be efficiently reversed to afford the opposite product diastereomer in high yield and selectivity.
