84504-57-4Relevant academic research and scientific papers
Synthesis and in vitro evaluation of 5,6,7,8,9,10-hexahydro-7,10- iminocyclohept[b]indoles: High-affinity ligands for the N,N'-di-o- tolylguanidine-labeled σ binding site
Mewshaw,Sherrill,Mathew,Kaiser,Bailey,Karbon
, p. 343 - 352 (1993)
A series of 5,6,7,8,9,10-hexahydro-7,10-iminocyclo[b]indoles substituted at the 5 and/or 11 positions was synthesized from tropinone. Affinity for σ binding sites was determined using [3H]-N,N'-di-o-tolylguanidine ([3H]DTG) and [sup
Bridged γ-Carbolines and Derivatives Possessing Selective and Combined Affinity for 5-HT2 and D2 Receptors
Mewshaw, Richard E.,Silverman, Lisa S.,Mathew, Rose M.,Kaiser, Carl,Sherrill, Ronald G.,et al.
, p. 1488 - 1495 (2007/10/02)
A series of 5,6,7,8,9,10-hexahydro-7,10-iminocycloheptindoles and 6,7,8,9,10,11-hexahydro-7,11-imino-5H-cyclooctindoles was prepared. Structural modifications of the lead compound, 11--5,6,7,8,9,10-hexahydro-7,10-iminocycl
STEREOCHEMICALLY COMPLEMENTARY REDUCTIONS OF INDOLES
Berger, Joel G.,Tahbaz, Pirouz,McPhail, Andrew T.,Onan, Kay D.
, p. 2469 - 2472 (2007/10/02)
Indoles containing 2, 3-fused bridged ring undergo highly stereoselective reduction to cis-fused derivatives with the endo-exo stereochemistry depending on choice of reducing agent.
5 Phenyl-1,3-alkano-1,2,3,4,4a,9b-hexahydropyrido [4,3-b]indoles
-
, (2008/06/13)
This invention relates to 5-phenyl-1,3-alkano-1,2,3,4,4a,9b-hexahydropyrido [4,3-b]indoles which are antidepressants useful in the treatment of mental depression.
