84508-51-0

Basic information

• Product Name: 2-BROMOETHANOL (1,2-13C2)
• Synonyms: 2-BROMOETHANOL (1,2-13C2);2-BROMOETHANOL-13C2;ETHYLENE-13C2 BROMOHYDRIN;2-BROMOETHANOL-13C2, 99 ATOM % 13C
• CAS NO: 84508-51-0
• Molecular Formula: C2H5BrO
• Molecular Weight: 126.98
• Mol File: 84508-51-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 56-57 °C/20 mmHg(lit.)
• Flash Point: 113 °C
• Appearance: /
• Density: 1.791 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.493(lit.)
• CAS DataBase Reference: 2-BROMOETHANOL (1,2-13C2)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOETHANOL (1,2-13C2)(84508-51-0)
• EPA Substance Registry System: 2-BROMOETHANOL (1,2-13C2)(84508-51-0)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2922 8/PG 2
• Hazardous Substances Data: 84508-51-0(Hazardous Substances Data)

Usage

Uses

2-Bromoethanol-13C2, is the labeled analogue of 2-Bromoethanol (B684735), an widely used intermediate in organic synthesis.

Upstream product

• 104700-12-1 ethylene glycol-¹³C₂ 

Relevant articles and documents

Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) is a carbodiimide coupling reagent commonly used for the preparation of amides from carboxylic acids and amines. Because of initial concerns regarding the genotoxicity of EDC and its use in GMP syntheses at Bristol Myers Squibb, the quantitation of residual EDC and its by-product N-(3-dimethylaminopropyl)-N′-ethylurea (EDU) by liquid chromatography–mass spectrometry (LCMS) impurity analysis was required. These analyses required the use of stable-isotope-labeled EDC and EDU to serve as internal standards. To meet this need, stable-isotope-labeled EDC 9 and EDU 10 were prepared from [1,2-13C2] ethylene glycol and [13C,15N] potassium cyanide in overall yields of 6% and 8%, respectively.