845252-02-0 Usage
General Description
Benzenemethanamine, 2,4-difluoro-a-methyl, (aS)- is a chemical compound that belongs to the class of organic compounds known as phenyl methyl amines. It is a chiral compound with a unique molecular structure which makes it suitable for certain pharmaceutical applications. This chemical is used in the synthesis of pharmaceutical drugs and is also used as a reagent in various chemical reactions. It has potential applications in the development of new drugs for the treatment of various medical conditions. Its properties make it a valuable compound in the field of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 845252-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,2,5 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 845252-02:
(8*8)+(7*4)+(6*5)+(5*2)+(4*5)+(3*2)+(2*0)+(1*2)=160
160 % 10 = 0
So 845252-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9F2N.ClH/c1-5(11)7-3-2-6(9)4-8(7)10;/h2-5H,11H2,1H3;1H/t5-;/m0./s1
845252-02-0Relevant articles and documents
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
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Page/Page column 158; 159, (2014/09/29)
The invention is directed to a formula (I), or a pharmamceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.