845252-02-0 Usage
Uses
Used in Pharmaceutical Synthesis:
Benzenemethanamine, 2,4-difluoro-α-methyl-, (αS)is used as a key intermediate in the synthesis of pharmaceutical drugs. Its unique molecular structure allows for the development of new drugs with specific therapeutic properties, addressing various medical conditions.
Used in Chemical Reactions:
Benzenemethanamine, 2,4-difluoro-a-methyl-, (aS)serves as a reagent in various chemical reactions, facilitating the synthesis of complex organic molecules. Its presence can enhance the efficiency and selectivity of these reactions, contributing to the advancement of organic chemistry.
Used in Drug Development:
Benzenemethanamine, 2,4-difluoro-α-methyl-, (αS)has potential applications in the development of new drugs for the treatment of various medical conditions. Its chiral nature and unique molecular structure make it a promising candidate for the design of innovative pharmaceutical agents with improved efficacy and selectivity.
Used in Pharmaceutical Research:
Benzenemethanamine, 2,4-difluoro-a-methyl-, (aS)is valuable in pharmaceutical research, where it can be used to study the structure-activity relationships of various drug candidates. Its unique properties can provide insights into the design and optimization of new therapeutic agents, advancing the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 845252-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,2,5 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 845252-02:
(8*8)+(7*4)+(6*5)+(5*2)+(4*5)+(3*2)+(2*0)+(1*2)=160
160 % 10 = 0
So 845252-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9F2N.ClH/c1-5(11)7-3-2-6(9)4-8(7)10;/h2-5H,11H2,1H3;1H/t5-;/m0./s1
845252-02-0Relevant academic research and scientific papers
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
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Page/Page column 158; 159, (2014/09/29)
The invention is directed to a formula (I), or a pharmamceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
PYRAZOLO [1,5-a] PYRIMIDINES USEFUL AS JAK2 INHIBITORS
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Page/Page column 75, (2009/08/14)
The present invention relates to compounds of formula (I) useful as selective inhibitors of JAK2 kinase. The invention also provides pharmaceutical acceptable compositions comprising said compounds and methods of using the compositions in the treatment of
