845266-47-9Relevant academic research and scientific papers
Enantioselective Synthesis of Bicyclopentane-Containing Alcohols via Asymmetric Transfer Hydrogenation
Vyas, Vijyesh K.,Clarkson, Guy J.,Wills, Martin
supporting information, p. 3179 - 3183 (2021/05/04)
Compounds a containing bicyclo[1.1.1]pentane (BCP) adjacent to a chiral center can be prepared with high enantiomeric excess through asymmetric transfer hydrogenation (ATH) of adjacent ketones. In the reduction step, the BCP occupies the position distant from the η6-arene of the catalyst. The reduction was applied to the synthesis of a BCP analogue of the antihistamine drug neobenodine.
Radical-induced metal-free alkynylation of aldehydes by direct C-H activation
Liu, Xuesong,Yu, Linqian,Luo, Mupeng,Zhu, Jidong,Wei, Wanguo
supporting information, p. 8745 - 8749 (2015/06/08)
A direct C(sp2)-H alkynylation of aldehyde C(O)-H bonds with hypervalent iodine alkynylation reagents provides ynones under metal-free conditions. In this method, 1-[(triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX) constitutes a
Oxaphospholes and bisphospholes from phosphinophosphonates and α,β-unsaturated ketones
Arkhypchuk, Anna I.,Orthaber, Andreas,Mihali, Viorica Alina,Ehlers, Andreas,Lammertsma, Koop,Ott, Sascha
supporting information, p. 13692 - 13704 (2013/10/22)
The reaction of a {W(CO)5}-stabilized phosphinophosphonate 1, (CO)5WPH(Ph)-P(O)(OEt)2, with ethynyl- (2 a-f) and diethynylketones (7-11, 18, and 19) in the presence of lithium diisopropylamide (LDA) is examined. Lithiated
Synthesis of 1,4-diethynyl- and 1,1,4,4-tetraethynylbutatrienes
Auffrant, Audrey,Diederich, Francois,Boudon, Corinne,Gisselbrecht, Jean-Paul,Gross, Maurice
, p. 3085 - 3105 (2007/10/03)
In this paper, we report the synthesis and opto-electronic properties of differentially substituted 1,4-diethynyl- and 1,1,4,4-tetraethynylbuta-1,2,3- trienes. These novel chromophores greatly extend the series of building modules for oxidative coupling,
