845271-69-4

Upstream product

• 1943-83-5 2-chloroethyl isothiocyanate 
• 851545-73-8 N-4-[3-chloro-4-(3-fluorobenzyloxy)-phenyl]-N-6-(2-phenyl-N-cyanoisourea)-quinazoline-4,6-diamine 
• 141-43-5 ethanolamine 

Relevant academic research and scientific papers

Quinazoline analogs as receptor tyrosine kinase inhibitors

This invention provides quinazoline analogs of Formula I: where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.