845273-58-7Relevant academic research and scientific papers
Novel mass tags for single nucleotide polymorphism detection
Birikh, Klara R.,Korshun, Vladimir A.,Bernad, Pablo L.,Malakhov, Andrei D.,Milner, Natalie,Khan, Safraz,Southern, Edwin M.,Shchepinov, Mikhail S.
, p. 2342 - 2350 (2008)
A new method suitable for single nucleotide polymorphism detection and other applications based on oligonucleotide probe extension has been developed. The method is based on mass spectrometry and utilizes a single surface for affinity purification of exte
Derivatised molecules for mass spectrometry
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Page 78, (2008/06/13)
Compounds of formula (IIa): are provided where:X is a group capable of being cleaved from the α-carbon atom to form an ion of formula (I')C is a carbon atom bearing a single positive charge or a single negative charge; The invention further provides compounds of formula (IIb): where:X is a counter-ion to C. The compounds of formula (IIa) and (IIb) may form ions of formula (I') by either cleaving the C-X bond between X and the α-carbon atoms in the case of the compounds of formula (IIa) or dissociating X in the case of compounds of formula (IIb).
