84532-72-9 Usage
Uses
Used in Pharmaceutical Industry:
6-METHOXY-5-(TRIFLUOROMETHYL)-1-NAPHTHOIC ACID is used as a key intermediate in the synthesis of various drugs and pharmaceutical products. Its unique structure allows for the development of new therapeutic agents with potential applications in treating a range of medical conditions.
Used in Research and Development:
6-METHOXY-5-(TRIFLUOROMETHYL)-1-NAPHTHOIC ACID has been studied for its potential biological activities, including anti-inflammatory and anti-tumor properties. Researchers are exploring its potential as a therapeutic agent in various disease models, aiming to understand its mechanism of action and optimize its efficacy.
Used as a Reference Standard in Analytical Chemistry:
6-METHOXY-5-(TRIFLUOROMETHYL)-1-NAPHTHOIC ACID is used as a reference standard in analytical chemistry, particularly in the development and validation of analytical methods for the detection and quantification of related compounds. Its well-defined chemical structure and properties make it an ideal candidate for such applications.
Used in Organic Synthesis:
6-METHOXY-5-(TRIFLUOROMETHYL)-1-NAPHTHOIC ACID is utilized in organic synthesis as a building block for the preparation of various organic compounds. Its unique functional groups and reactivity make it a valuable component in the synthesis of complex organic molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 84532-72-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,3 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 84532-72:
(7*8)+(6*4)+(5*5)+(4*3)+(3*2)+(2*7)+(1*2)=139
139 % 10 = 9
So 84532-72-9 is a valid CAS Registry Number.
84532-72-9Relevant academic research and scientific papers
Degradation kinetics of tolrestat
Lee,Lee
, p. 628 - 633 (2007/10/02)
Under stressed conditions, hydrolysis of the trifluoromethyl moiety of tolrestat (1) to the dicarboxylic acid analogue (2) is the major degradation pathway in solution; > C = S bond hydrolysis of the thioamide moiety with formation of the oxo analogue (3) is the major solid-state degradation pathway. Rotamerization and degradation reactions in solution occur simultaneously and follow pseudo first-order kinetics. No appreciable buffer effect on the degradation of tolrestat is observed. The pH-rate profile exhibits specific acid catalysis (K(H)) and neutral water catalysis (k(o)). When tolrestat in solution and solid state is exposed to fluorescent and UV light, degradation reactions generate similar products to those found in the thermal reaction. No oxygen effect on the degradation reaction is observed.
6-(Lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxaldehydes
-
, (2008/06/13)
A process and intermediates for preparing 6-(lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxylic acid derivatives are disclosed. The derivatives are useful for preparing aldose reductase inhibitors. With reference to the process, 1,1,1-trifluoro-5-(2-methylphenyl)-2,3-pentadione 3-oxime is cyclized to give a key intermediate 3,4-dihydro-1-hydroxy-5-methyl-1-(trifluoromethyl)-2(1H)-naphthalenone oxime; and 3,4-dihydro-1-hydroxy-5-methyl-1-(trifluoromethyl)-2(1H)-naphthalenone is aromatized to 5-methyl-1-(trifluoromethyl)-2-naphthalenol with a dehydrating agent.
