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"Z-Trp(Mtr)-Ala-Val-Gly-OBut" is a peptide compound consisting of five amino acids: Z-protected tryptophan (Trp) with a methyltrityl (Mtr) group, alanine (Ala), valine (Val), and glycine (Gly), with a tert-butyl (OBut) protecting group on the C-terminus. This sequence is commonly used in peptide synthesis, where the Z group is a protecting group that shields the amino group of tryptophan from unwanted reactions, and the OBut group protects the carboxyl group of the peptide's C-terminus. The Mtr group is a photosensitive protecting group that can be removed by UV light, which is useful for stepwise synthesis of larger peptides. The specific sequence and protective groups indicate that Z-Trp(Mtr)-Ala-Val-Gly-OBut is likely an intermediate in the synthesis of a larger peptide or protein, where the protective groups will be removed at appropriate stages to allow for further reactions or folding into a functional protein.

84552-54-5

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84552-54-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84552-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,5 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 84552-54:
(7*8)+(6*4)+(5*5)+(4*5)+(3*2)+(2*5)+(1*4)=145
145 % 10 = 5
So 84552-54-5 is a valid CAS Registry Number.

84552-54-5Relevant academic research and scientific papers

4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr): a New Amino and Imidazole Protecting Group in Peptide Synthesis

Wakimasu, Mitsuhiro,Kitada, Chieko,Fujino, Masahiko

, p. 2766 - 2779 (2007/10/02)

The 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group was introduced as a protecting group for the amino function, especially the ε-amino function of lysine, and the imidazole ring of histidine.The Nε-Mtr group was removable by dilute methanesulfonic acid-containing trifluoroacetic acid-thioanisole, but was stable to trifluoroacetic acid or catalytic hydrogenation.The Nim-Mtr group was removable by trifluoroacetic acid-dimethylsulfide or 1-hydroxybenzotriazole, but was more stable than the Nim-Tos or the Nim-Mbs group with triethylamine.To examine the usefulness of the Mtr group as a protecting group for use in peptide synthesis, mastoparan X and chicken gastrin releasing peptide (c-GRP) were synthesized, and this group was found to be very convenient for general solution synthesis.In particular, the introduction of Lys(Mtr) made possible a new strategy in peptide synthesis.Keywords-4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); Nε-4-methoxy-2,3,6-trimethylbenzenesulfonyllysine; Nim-4-methoxy-2,3,6-trimethylbenzenesulfonylhistidine; methanesulfonic acid-trifluoroacetic acid-thioanisole deprotection; trifluoroacetic acid-dimethylsulfide deprotection; mastoparan X; chicken gastrin releasing peptide

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