(R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid, also known as D-aspartate derivative, is a photolabelled compound that exhibits high affinity for Na+/K+ glutamate transporters and acts as an effective ligand for NMDA receptors. It plays a crucial role in the study and understanding of glutamate transport and NMDA receptor function in the central nervous system.
845555-94-4
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Basic information
- Product Name: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid
- Synonyms: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid;MNI-caged-D-aspartate
- CAS NO:845555-94-4
- Molecular Formula: C13H15N3O6
- Molecular Weight: 309.2747
- EINECS: N/A
- Product Categories: N/A
- Mol File: 845555-94-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Store at -20°C
- Solubility: N/A
- CAS DataBase Reference: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid(CAS DataBase Reference)
- NIST Chemistry Reference: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid(845555-94-4)
- EPA Substance Registry System: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid(845555-94-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 845555-94-4(Hazardous Substances Data)
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845555-94-4 Usage
Uses
Used in Pharmaceutical Industry:(R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid is used as a research compound for studying the mechanisms of glutamate transport and NMDA receptor function. Its ability to act as an effective ligand for NMDA receptors makes it a valuable tool in the development of drugs targeting neurological disorders associated with glutamate dysregulation.
Used in Neuroscientific Research:
In the field of neuroscientific research, (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid serves as a valuable probe for investigating the role of high-affinity Na+/K+ glutamate transporters in neurotransmission and synaptic plasticity. This knowledge can contribute to the understanding of various neurological conditions and the development of potential therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 845555-94-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,5,5 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.Calculate Digit Verification of CAS Registry Number 845555-94:
(8*8)+(7*4)+(6*5)+(5*5)+(4*5)+(3*5)+(2*9)+(1*4)=204
204 % 10 = 4
So 845555-94-4 is a valid CAS Registry Number.
845555-94-4Upstream product
845555-94-4Downstream Products
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(R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoicacid
