845617-19-8

Basic information

• Product Name: 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Methyl ester
• Synonyms: 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Methyl ester
• CAS NO: 845617-19-8
• Molecular Formula: C₁₂H₁₃F₃O₅S
• Molecular Weight: 326.2888296
• Mol File: 845617-19-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 422.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.343±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Methyl ester(845617-19-8)
• EPA Substance Registry System: 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Methyl ester(845617-19-8)

Safety Data

• Hazardous Substances Data: 845617-19-8(Hazardous Substances Data)

Upstream product

• 212556-43-9 1,1,1-trifluoropropan-2-yl trifluoromethanesulfonate 
• 101371-44-2 methyl 2-hydroxy-5-(methylsulfonyl)benzoate 

Downstream Products

• 845617-20-1 5-Methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-benzoic acid methyl ester 
• 845617-21-2 5-methanesulfonyl-2-((R)-2,2,2-trifluoro-1-methyl-ethoxy)-benzoic acid methyl ester 

Relevant articles and documents

Substituted phenyl methanone derivatives

The present invention relates to compounds of formula I wherein R1, R2, R3, n, and m, are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. These compounds are good inhibitors

[4-(HETEROARYL) PIPERAZIN-1-YL]-(2,5-SUBSTITUTED -PHENYL)METHANONE DERIVATIVES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

The present invention relates to compounds of the general formula (I) wherein R1 is-OR1’,-SR1’ or is a heterocycloalkyl group; R1’ is lower alkyl, lower alkyl substituted by halogen or is -(CH2)n