845617-58-5 Usage
Class
Piperazine compounds
Derivative
Phenylpiperazine
Industry
Pharmaceutical
Potential use
Development of new drugs
Target
Serotonin receptor antagonist
Preclinical studies
Shown promising results
Additional activity
Dopamine receptor antagonist
Structural features
Presence of fluorine and ethylsulfonyl groups
Pharmacological properties
Influenced by fluorine and ethylsulfonyl groups
Bioactivity
Potential for therapeutic applications
Ongoing research
Investigating therapeutic applications and drug development potential
Check Digit Verification of cas no
The CAS Registry Mumber 845617-58-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,6,1 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 845617-58:
(8*8)+(7*4)+(6*5)+(5*6)+(4*1)+(3*7)+(2*5)+(1*8)=195
195 % 10 = 5
So 845617-58-5 is a valid CAS Registry Number.
845617-58-5Relevant articles and documents
CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS
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Page/Page column 82, (2009/03/07)
The present invention relates to compounds of formula (I) for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
