84562-37-8

Basic information

• Product Name: 2,6-Dichloro-N'-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine
• Synonyms: 2,6-Dichloro-N'-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine
• CAS NO: 84562-37-8
• Molecular Weight: 334.032
• Mol File: 84562-37-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-Dichloro-N'-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-N'-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine(84562-37-8)
• EPA Substance Registry System: 2,6-Dichloro-N'-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine(84562-37-8)

Safety Data

• Hazardous Substances Data: 84562-37-8(Hazardous Substances Data)

Upstream product

• 99-30-9 4-nitro-2,6-dichloroaniline 
• 10203-08-4 3,5-dichlorobenzaldehyde 
• 609-20-1 2,6-dichloro-p-phenylenediamine 

Downstream Products

• 85103-67-9 2,6-Dichloro-N'-(3,5-dichloro-benzyl)-benzene-1,4-diamine 
• 92366-70-6 N'-[2,6-Dichloro-4-(3,5-dichloro-benzylamino)-phenyl]-N,N-dimethyl-formamidine 

Relevant articles and documents

N2-(4-Substituted-2,6-dichlorophenyl)-N1,N1-dimethylformamidines as Antihypertensive and Diuretic Agents

The synthesis of a series of N2--2,6-dichlorophenyl>-N1,N1-dimethylformamidines that caused marked blood pressure lowering and/or diuresis in spontaneously hypertensive rats (SHR) is reported.Diuretic activity was not always associated with acute antihypertensive activity.Central nervous system effects, most notably sedation, were observed.Compound 9d, which lowered arterial blood pressure 37 mmHg in SHR when dosed at 100 mg/kg, was further evaluated in chronic hypertensive dogs because of apparent minimal CNS effects.A reduction in arterial blood pressure of 32 mmHg at 1.0 mg/kg during a 6-h postdosing interval was observed.This response was unrelated to α- or β-adrenergic blockade, angiotensin I antagonism, or neuronal or ganglionic blockade.CNS effects were also observed.