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Usage

Uses

Used in Pharmaceutical Industry:
6-ethynyl-2-Pyridinemethanol is used as an intermediate in the synthesis of various pharmaceuticals for its ability to introduce the pyridine moiety into complex molecular structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 6-ethynyl-2-Pyridinemethanol is used as a precursor in the production of agrochemicals, such as pesticides and herbicides, due to its reactivity and capacity to form stable and effective compounds.
Used in Electronic Materials Manufacturing:
6-ethynyl-2-Pyridinemethanol is utilized in the manufacturing of electronic materials, where its unique chemical structure and reactivity are harnessed to create components with specific electronic properties, contributing to the advancement of electronic devices and technologies.
Overall, 6-ethynyl-2-Pyridinemethanol's wide range of applications in the pharmaceutical, chemical, and electronic industries is a testament to its unique chemical structure and reactivity, making it an indispensable compound in modern chemical research and product development.

Upstream product

• 33674-96-3 2-bromo-6-(hydroxymethyl)pyridine 
• 1066-54-2 trimethylsilylacetylene 
• 147133-46-8 6-bromopyridin-2-ylmethyl acetate 
• 1253283-52-1 (6-((trimethylsilyl)ethynyl)pyridin-2-yl)methanol 

Relevant academic research and scientific papers

Addressing the poly- to oligo-ketone selectivity in styrene carbonylation catalyzed by palladium/bpy complexes. effect of the 6-alkyl substitution

Two series of organometallic Pd complexes, namely, (i) [Pd(CH 3)(CH3CN)(N-N′)][PF6] and (ii) [Pd(CH3)(N-N′)2][PF6], with a range of 6-alkyl-substituted-2,2′-bipyridine ligands, including the new 6-(1-methoxyethyl)-2,2′-bipyridine, in both racemic and enantiopure form, and 2-(methoxymethyl)-6-(1H-1,2,3-triazol-1-yl)pyridine, have been studied. 6-(1-Methoxyethyl)-2,2′-bipyridine was synthesized both in racemic and in the opposite homochiral enantiomeric forms by two stereocomplementary chemoenzymatic procedures. The characterization of the new complexes, both in solid state and in solution, provides evidence for the formation of a unique isomer featuring the methyl ligand trans to the Pd-N bond of the substituted pyridine ring. For the complex with the bpy ligand having the sec-butyl substituent a cyclometalation reaction with the release of methane occurs, leading the substituted bpy to act as a terdentate N-N′-C ligand. Complexes of series ii feature one chelate N-N′ ligand, while the other one is coordinated to Pd in a monodentate fashion. In solution a fluxional process that makes equivalent the two N-N′ ligands is present, and the static 1H NMR spectra correspond to an averaged structure where palladium is a stereogenic center. All these complexes behave as catalysts for styrene carbonylation, yielding CO/styrene oligoketones, which are optically active when catalysts containing chiral, enantiomerically pure, ligands are applied. For both series of complexes the reactivity with labeled CO has been investigated, leading to the formation of the corresponding Pd-acetyl species, with that for complexes of series ii featuring both N-N′ molecules bonded to the same metal center.

CHEMICAL COMPOUNDS

The present invention discloses pyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such pyrimidine derivatives are useful in the treat

4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES

The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor a