845675-35-6 Usage
Purpose
Pharmaceutical drug for the treatment of ovarian cancer
Drug class
Poly (ADP-ribose) polymerase (PARP) inhibitors
Mechanism of action
Blocks the enzyme involved in repairing damaged DNA in cancer cells, leading to the death of cancer cells
Clinical trial results
Promising
Regulatory approval
For certain types of ovarian cancer
Check Digit Verification of cas no
The CAS Registry Mumber 845675-35-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,6,7 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 845675-35:
(8*8)+(7*4)+(6*5)+(5*6)+(4*7)+(3*5)+(2*3)+(1*5)=206
206 % 10 = 6
So 845675-35-6 is a valid CAS Registry Number.
845675-35-6Relevant academic research and scientific papers
PYRAZOLE CARBOXAMIDES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1
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, (2010/02/10)
Pyrazole carboxamides of structural formula (I) are selective inhibitors of the 11beta-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin r