84579-99-7Relevant academic research and scientific papers
Crystalline penicillin ester intermediate
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, (2008/06/13)
Crystalline chloromethyl 6-(alpha-1-methoxycarbonylpropen-2-ylaminophenylacetamido)penicillanate as an intermediate to antibacterial agents.
Process for the preparation of penicillanic acid esters
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, (2008/06/13)
A process for the preparation of chloromethyl esters of penicillanic acids, using iodochloromethane or bromochloromethane and a tetraalkylammonium salt of the penicillanic acid, and their use in processes for the synthesis of penicillanic acid esters, using a halomethyl ester and the tetraalkylammonium salt of the penicillanic acid, which readily hydrolyze in vivo to antibacterial penicillins and the beta-lactamase inhibitor penicillanic acid sulfone.
