845797-37-7

Upstream product

• 845797-36-6 benzyl (2S,3S)-2-(2-(2-(3-ethylureido)-5-(trifluoromethyl)benzamido)acetamido)-3-hydroxyhex-4-ynylcarbamate 

Downstream Products

• 845797-39-9 TFA salt of 1-(2-((2-((2S,3S)-3-hydroxy-1-(neopentylamino)hexan-2-ylamino)-2-oxoethyl)carbamoyl)-4-(trifluoromethyl)phenyl)-3-ethylurea 
• 845797-35-5 TFA salt of 1-(2-((2-((2S,3S)-3-hydroxy-1-(isobutylamino)hexan-2-ylamino)-2-oxoethyl)carbamoyl)-4-(trifluoromethyl)phenyl)-3-ethylurea 

Relevant academic research and scientific papers

Lactams of alkylated acyclic diamine derivatives as modulators of chemokine receptor activity

The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis.

N-ALKYLATED DIAMINOPROPANE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present application describes modulators of MCP-1 of formula (I), or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis.