845829-91-6

Usage

Uses

Used in Pharmaceutical Research and Development:
Benzenemethanamine, 4-bromo-2-fluoro-.alpha.-methyl-, hydrochloride (1:1), (.alpha.R)is used as a key intermediate in the synthesis of pharmaceutical drugs. Its unique chemical structure allows it to be incorporated into the development of new medications, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Synthesis:
In addition to its pharmaceutical applications, Benzenemethanamine, 4-bromo-2-fluoro-.alpha.-methyl-, hydrochloride (1:1), (.alpha.R)may also have potential uses in chemical synthesis. Its versatile structure can be employed in the creation of various chemical compounds, contributing to advancements in the field of organic chemistry.
Used in Organic Chemistry Research:
Benzenemethanamine, 4-bromo-2-fluoro-.alpha.-methyl-, hydrochloride (1:1), (.alpha.R)-'s unique properties and reactivity make it a valuable tool for researchers in the field of organic chemistry. It can be used to study reaction mechanisms, explore new synthetic routes, and develop innovative methodologies for the synthesis of complex organic molecules.

Upstream product

• 925215-00-5 N-[(1R)-1-(4-bromo-2-fluorophenyl)ethyl]-2-methylpropane-2-sulfinamide 
• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 578729-14-3 2-methyl-propane-2-sulfinic acid [(R)-1-(4-bromo-2-fluoro-phenyl)-ethyl]-amide 
• 845829-92-7 tert-butyl (1R)-1-(4-bromo-2-fluorophenyl)ethylcarbamate 
• 935431-10-0 N-[(1E)-(4-bromo-2-fluorophenyl)methylidene]-2-methylpropane-2-sulfinamide 

Relevant academic research and scientific papers

NEW BIARYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.

NEW BIARYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.

Development of orally bioavailable and CNS penetrant biphenylaminocyclopropane carboxamide bradykinin B1 receptor antagonists

A series of biphenylaminocyclopropane carboxamide based bradykinin B 1 receptor antagonists has been developed that possesses good pharmacokinetic properties and is CNS penetrant. Discovery that the replacement of the trifluoropropionamide in t

SULFONYL SUBSTITUTED N-(BIARYLMETHYL) AMINOCYCLOPROPANECARBOXAMIDES

N-(Sulfonyloxybiarylmethyl) aminocyclopropanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.

N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives

N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.