845879-99-4 Usage
Uses
Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[[2-(phenylthio)ethoxy]methyl]is used as an antiviral agent for the treatment of certain viral infections. Its antiviral properties are attributed to its ability to inhibit viral replication and reduce the severity of the infection.
Used in Oncology:
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[[2-(phenylthio)ethoxy]methyl]is used as an antineoplastic agent for the treatment of certain types of cancer. Its antineoplastic activity is due to its ability to interfere with cancer cell growth and proliferation, thereby inhibiting tumor development and spread.
Check Digit Verification of cas no
The CAS Registry Mumber 845879-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,8,7 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 845879-99:
(8*8)+(7*4)+(6*5)+(5*8)+(4*7)+(3*9)+(2*9)+(1*9)=244
244 % 10 = 4
So 845879-99-4 is a valid CAS Registry Number.
845879-99-4Relevant academic research and scientific papers
Liu, Xue-Jun,Chen, Ru-Yu,Bai, Dong-Lu
, p. 543 - 548 (2004)
A series of novel 1-(2′-alkyl(or phenyl)-thioethoxy)methyl-5-fluorouracils (6) were synthesized in three steps from 5-fluorouracil. They were oxidized into sulfoxide (7) and sulfone (8) derivatives by NaIO4 and H2O2 30%/DEAD (diethyl azodicarboxylate), respectively, in high yields. In order to obtain structural information, sulfoxide 7g was characterized by X-ray diffraction analysis. The preliminary bioassay indicated that the compounds 6a and 7g exhibit potential antitumor activity.
