845882-10-2Relevant academic research and scientific papers
Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
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Page/Page column 18, (2010/02/10)
Pentafluorosulfanylphenyl-substituted benzoylguanidines of the formulae I and II in which R1, R1′, R2, R2′, R3, R3′, R4 and X have the meanings indicated in the claims, are suitable as antiarrhythmic medicaments with a cardioprotective component for the prophylaxis of infarction and treatment of infarction and for the treatment of angina pectoris. They also inhibit preventively the pathophysiological processes associated with the development of ischemia-induced damage, especially in the triggering of ischemia-induced cardiac arrhythmias.
