845890-34-8

Basic information

• Product Name: Benzenepropanoic acid, 4-(3-thienyl)-
• CAS NO: 845890-34-8
• Molecular Formula: C13H12O2S
• Molecular Weight: 232.303
• Mol File: 845890-34-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 4-(3-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 4-(3-thienyl)-(845890-34-8)
• EPA Substance Registry System: Benzenepropanoic acid, 4-(3-thienyl)-(845890-34-8)

Safety Data

• Hazardous Substances Data: 845890-34-8(Hazardous Substances Data)

Upstream product

• 845890-31-5 benzyl 3-(4-bromophenyl)propionate 
• 1643-30-7 3-(4-bromophenyl)propionic acid 
• 6165-69-1 Thien-3-ylboronic acid 
• 872-31-1 3-Bromothiophene 
• 166316-48-9 4-(2-carboxyethyl)benzeneboronic acid 

Relevant articles and documents

Photoluminescence Enhancement of Carbon Dots by Surfactants at Room Temperature

During the past decade, increasing attention has been paid to fluorescent carbon dots (CDs) due to their unique photoluminescence (PL) properties. As synthetic methods gradually develop, many post-functionalization strategies have been developed to enhance the PL of CDs. However, in most cases, the PL enhancement was less than 10-fold with multistep modification processes. In this work, a facile and efficient post-functionalization strategy was successfully applied to enhance the PL intensity of CDs dramatically up to 69 times by surfactants at room temperature for the first time. Furthermore, the mechanism of surfactant-induced PL enhancement of CDs was investigated and in vivo bioimaging was performed. The results demonstrated that electrostatic/non-electrostatic interactions between CDs and surfactants could effectively lower the vibration and rotation of CDs, increase radiative decay processes and, thus, enhance the PL of CDs. This finding may provide new insights into the strategies for enhancing the PL of CDs, further broadening their potential applications.

Synthesis method of succinic acid derivative or 3 -arylpropionic acid (by machine translation)

The invention discloses a synthesis method of a succinic acid derivative or 3 -arylpropionic acid, which comprises the following steps: adding a base in a drying reaction tube and CO removing CO. 2 The reaction is carried out under the irradiation of visible light, the reaction is carried out under visible light irradiation, and then separation and purification are carried out to obtain the butanedioic acid derivative or 3 -arylpropionic acid product; the base comprises sodium tert-butoxide, potassium tert-butoxide, lithium tert-butyl alcohol and 4 - potassium carbonate; and the reaction substrate comprises an acrylate compound or an aryl vinyl compound. CO can be induced by visible light. 2 The scheme provided by the invention is mild in reaction condition and wide in reaction 3 - substrate selectivity, and the reaction substrate is wide in selectivity, the raw materials are cheap and easily available, and the method has a good industrial application prospect. (by machine translation)

2-SUBSTITUTED BENZOIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS

Therapeutically active anthranilic acid derivatives of Formula (I) wherein R1, R2 and Z are as defined in the specification, processes for the preparation of said derivatives, pharmaceutical formulations containing the active compounds and the use of the compounds in therapy, particularly in the treatment of diseases in which under-activation of the HM74A receptor contributes to the disease or in which activation of the receptor will be beneficial, are disclosed.