845894-45-3

Upstream product

• 89160-10-1 methyl 7,7-dibromo-6,7-dideoxy-2,3,4-tri-O-benzyl-α-D-gluco-hept-6-enopyranoside 
• 845894-44-2 (1R,3R,4R,5S,6S)-4,5,6-Tris-benzyloxy-2,2-difluoro-3-prop-1-ynyl-cyclohexanol 
• 845894-43-1 (3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-difluoromethylene-6-prop-1-ynyl-tetrahydro-pyran 
• 845894-40-8 Acetic acid (3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-prop-1-ynyl-tetrahydro-pyran-2-yl ester 
• 845894-39-5 (2S,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-methoxy-6-prop-1-ynyl-tetrahydro-pyran 
• 845894-42-0 (3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-prop-1-ynyl-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

Synthesis of gem-difluorocarba-d-glucose: A step further in sugar mimesis

A rearrangement strategy was used for the synthesis of α- and β-gem-difluorocarba-D-glucose, which are close congeners of α- and β-D-glucose, in which the endocyclic oxygen atom has been replaced by a gem-difluoromethylene group (see scheme). The two anom