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3-[2-[2-cyclopentyl-6-(4-diMethylphosphorylanilino)purin-9-yl]ethyl]phenol, also known as CX-5461, is a small molecule inhibitor that targets RNA polymerase I transcription. It is a promising candidate for cancer therapeutics due to its ability to inhibit the growth of various cancer cell lines by disrupting the binding of the SL1 transcription factor to the rDNA promoter, leading to the activation of p53-dependent nucleolar stress response and ultimately inducing cell death in cancer cells.

845895-51-4

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845895-51-4 Usage

Uses

Used in Cancer Research and Therapeutics:
3-[2-[2-cyclopentyl-6-(4-diMethylphosphorylanilino)purin-9-yl]ethyl]phenol is used as a potential anti-cancer agent for its ability to inhibit the growth of various cancer cell lines. It functions by disrupting the binding of the SL1 transcription factor to the rDNA promoter, which leads to the activation of p53-dependent nucleolar stress response and induces cell death in cancer cells.
Used in Pharmaceutical Industry:
3-[2-[2-cyclopentyl-6-(4-diMethylphosphorylanilino)purin-9-yl]ethyl]phenol is used as a novel compound in the development of cancer therapeutics. Its unique mechanism of action targeting RNA polymerase I transcription and inducing cell death in cancer cells makes it a valuable asset in the search for new and effective cancer treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 845895-51-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,8,9 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 845895-51:
(8*8)+(7*4)+(6*5)+(5*8)+(4*9)+(3*5)+(2*5)+(1*1)=224
224 % 10 = 4
So 845895-51-4 is a valid CAS Registry Number.

845895-51-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[2-[2-cyclopentyl-6-(4-dimethoxyphosphorylanilino)purin-9-yl]ethyl]phenol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:845895-51-4 SDS

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