845973-56-0

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-2-[[3-[[(2R)-2-(methoxymeth yl)-1-pyrrolidinyl]carbonyl]-5-methylbenzoyl]amino]propyl]-, 1,1-dimethylethyl ester, (2R)-
• CAS NO: 845973-56-0
• Molecular Formula: C33H44F2N4O6
• Molecular Weight: 630.732
• Mol File: 845973-56-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-2-[[3-[[(2R)-2-(methoxymeth yl)-1-pyrrolidinyl]carbonyl]-5-methylbenzoyl]amino]propyl]-, 1,1-dimethylethyl ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-2-[[3-[[(2R)-2-(methoxymeth yl)-1-pyrrolidinyl]carbonyl]-5-methylbenzoyl]amino]propyl]-, 1,1-dimethylethyl ester, (2R)-(845973-56-0)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-2-[[3-[[(2R)-2-(methoxymeth yl)-1-pyrrolidinyl]carbonyl]-5-methylbenzoyl]amino]propyl]-, 1,1-dimethylethyl ester, (2R)-(845973-56-0)

Safety Data

• Hazardous Substances Data: 845973-56-0(Hazardous Substances Data)

Upstream product

• 205445-52-9 (2S)-2-[(tert-butoxycarbonyl)amino]-3-(3,5-difluorophenyl)propanoic acid 
• 845544-11-8 C₃₉H₄₃F₂N₃O₄ 
• 845544-12-9 C₂₅H₃₁F₂N₃O₄ 
• 845546-59-0 C₂₅H₃₃F₂N₃O₃ 
• 845543-59-1 C₂₄H₂₃F₂NO₂ 
• 845543-60-4 2-dibenzylamino-3-(3,5-difluoro-phenyl)-propan-1-ol 
• 473567-47-4 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(3,5-difluorophenyl)propanoate 
• 845543-61-5 (S)-N,N-dibenzyl-3,5-difluorophenyl-alaninal 
• 845973-54-8 C₄₀H₅₀F₂N₄O₆ 

Relevant articles and documents

Piperazine sulfonamide BACE1 inhibitors: Design, synthesis, and in vivo characterization

With collaboration between chemistry, X-ray crystallography, and molecular modeling, we designed and synthesized a series of novel piperazine sulfonamide BACE1 inhibitors. Iterative exploration of the non-prime side and S2′ sub-pocket of the enzyme culmin