846055-82-1

Basic information

• Product Name: 2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester
• Synonyms: 2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester;methyl 2-(2-methoxyvinyl)-6-nitrobenzoate;JVHIZFOEWLXRJA-UHFFFAOYSA-N
• CAS NO: 846055-82-1
• Molecular Formula: C₁₁H₁₁NO₅
• Molecular Weight: 237.20874
• Product Categories: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 846055-82-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 370.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.271±0.06 g/cm3(Predicted)
• Solubility: DCM, Methanol
• CAS DataBase Reference: 2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester(846055-82-1)
• EPA Substance Registry System: 2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester(846055-82-1)

Safety Data

• Hazardous Substances Data: 846055-82-1(Hazardous Substances Data)

Usage

Uses

2-(2-Methoxyvinyl)-6-nitrobenzoic Acid Methyl Ester is an intermediate in the synthesis of Ropinirole (R641000), an antiparkinsonian agent.

Upstream product

• 142314-70-3 methyl 2-formyl-6-nitrobenzoate 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 13506-76-8 2-methyl-6-nitrobenzoic acid 
• 61940-22-5 methyl 2-methyl-6-nitrobenzoate 
• 61940-21-4 methyl 2-(bromomethyl)-6-nitrobenzoate 

Downstream Products

• 1056123-60-4 methyl 2-nitro-6-(2-oxoethyl)benzoate 
• 1233858-24-6 8-nitro-2-(3-(trifluoromethyl)phenyl)-3,4-dihydroisoquinolin-1(2H)-one 
• 1233858-26-8 8-amino-2-(3-(trifluoromethyl)phenyl)-3,4-dihydroisoquinolin-1(2H)-one 
• 1233858-14-4 N-(1-oxo-2-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinolin-8-yl)pyrazine-2-carboxamide 

Relevant articles and documents

NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF

The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.

PHTHALAZINONE AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for e