84646-50-4 Usage
Molecular Structure
Pyrrolopyridine derivative
Potential Activity
Antineoplastic (cancer treatment potential)
Mechanism of Action
Selectively inhibits the WDR5-MLL interaction, disrupting the MLL complex and leading to downregulation of genes involved in leukemia cell proliferation and development
Current Status
Being studied for potential therapeutic applications in the treatment of leukemia and other types of cancer
Check Digit Verification of cas no
The CAS Registry Mumber 84646-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,6,4 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 84646-50:
(7*8)+(6*4)+(5*6)+(4*4)+(3*6)+(2*5)+(1*0)=154
154 % 10 = 4
So 84646-50-4 is a valid CAS Registry Number.
84646-50-4Relevant academic research and scientific papers
AZAINDOLINE DERIVATIVES: 62.* SYNTHESIS AND TRANSFORMATIONS OF CONDENSED THREE-RING SYSTEMS THAT INCLUDE A 5-AZAINDOLINE FRAGMENT
Azimov, V. A.,Bychikhina, N. N.,Yakhontov, L. N.
, p. 1061 - 1064 (2007/10/02)
The reaction of 7-carbamoyl and 7-cyano-6-chloro-5-azaindolines with hydrazine leads to the formation of pyrrolopyrazolopyridine, whereas the reaction of 7-carbamoyl-5-azaindolines with dimethylformamide diethylacetal gives pyrrolopyr
