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Usage

Uses

Used in Pharmaceutical Industry:
Decinnamoyltaxinine J is used as an anticancer agent for its potent cytotoxic effects against specific cancer cell lines. It may be employed in the development of new cancer treatments, offering a valuable addition to the existing arsenal of drugs for cancer therapy.
Used in Therapeutic Applications:
Decinnamoyltaxinine J is used as an anti-inflammatory and antioxidant agent due to its demonstrated properties in research. These properties may contribute to its potential use in treating various diseases and conditions where inflammation and oxidative stress play a significant role.

Upstream product

• 108-24-7 acetic anhydride 
• 126585-87-3 triacetoxy-7β,9α,10β trihydroxy-2α,5α,13α taxadiene-4(20),11 

Relevant academic research and scientific papers

Plantes de Nouvelle-Caledonie. 124. Taxanes isoles des ecorces de tronc d'Austrotaxus spicata Compton (Taxacees)

Eighteen taxane-type diterpenes have been isolated from the trunk bark of Austrotaxus spicata: thirteen are alkaloids.Eight compounds have an exocyclic-4(20) methylene group: austrospicatine, 2'-desacetyl-austrospicatine, 2'-desacetoxyaustrospicatine, already found in the leaves of the same plant, comptonine, spicaledonine, 7β,9α,10β-triacetoxy 2α,5α,13α-trihydroxy 4(20),11-taxadiene, 2',13α,14β-tridesacetylaustrotaxine and 7β,9α-diacetoxy 5α,13α,14β-trihydroxy 10-oxo 4(20),11-taxadiene which are described here for the first time.The ten other compounds have an epoxide group in position 4(20): spicataxine, 9α-acetyl 10β-desacetylspicataxine, spicatine, 9α-acetyl 10β-desacetylspicatine, 10β-desacetylspicatine, nicaustrine, N-demethylnicaustrine, nicotaxine, 5α-O-(3'-methylamino 3'-phenylpropionyl)nicotaxine and 5α-O-(3'-amino 3'-phenylpropionyl)nicotaxine: all these products are new, the last five are original by owning a nicotinic substituent.The structures have been established from the spectral data, mainly from MS, 1H and 13C NMR spectra.