846542-07-2

Upstream product

• 496877-73-7 (S)-4-Benzyl-3-[(2S,3R)-2,4-bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-butyl]-5,5-dimethyl-oxazolidin-2-one 
• 496877-72-6 (2'S,3'R,4S)-4-benzyl-3-(2',4'-bis(benzyloxy)-3'-(tert-butyldimethylsilanyloxy)butyryl)-5,5-dimethyloxazolidin-2-one 
• 496877-71-5 (2'S,3'R,4S)-4-benzyl-3-(2',4'-bis(benzyloxy)-3'-hydroxybutyryl)-5,5-dimethyloxazolidin-2-one 
• 496877-70-4 (S)-N-α-benzyloxyacetyl-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 60656-87-3 benzyloxyacetoaldehyde 
• 846542-04-9 (2'S,3'R,4S)-4-benzyl-3-[2',4'-bis(benzyloxy)-3'-(tert-butyldimethylsilanyloxy)-1'-hydroxybutyl]-5,5-dimethyloxazolidin-2-one 
• 163041-09-6 (2S,3R)-2,4-bis(benzyloxy)-3-(tert-butyldimethylsilanyloxy)butyraldehyde 

Downstream Products

• 37111-85-6 2,4,6-tri-O-benzyl-α,β-D-galactopyranose 
• 496877-76-0 (3R,4S,5R,6R)-3,5-bis(benzyloxy)-6-benzyloxymethyl-4-hydroxytetrahydropyran-2-one 

Relevant academic research and scientific papers

A SuperQuat glycolate aldol approach to the asymmetric synthesis of hexose monosaccharides

A stereoselective two-carbon homologation protocol has been developed and applied to the asymmetric synthesis of the hexose monosaccharides D-galactose, D-fucose, D-idose, D-6-deoxyidose, D-talose and D-6-deoxytalose.

The asymmetric synthesis of D-galactose via an iterative syn-glycolate aldol strategy

The asymmetric synthesis of D-galactose has been completed in eight steps and in >14% yield from simple starting materials via an iterative syn-glycolate aldol strategy.