846549-86-8

Upstream product

• 108944-89-4 (4aR,8aR)-(+)-1-methylene-2-oxo-5,5,8a-trimethyldecahydronaphthalene 
• 2237-21-0 (((2-bromo-1,4-phenylene)bis(oxy))bis(methylene))dibenzene 
• 108-24-7 acetic anhydride 
• 253269-97-5 (1R,4aR,8aR)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-tri-methyl-2-oxo-trans-naphthalene-1-methanol 
• 59684-77-4 (+/-)-8-oxo-12-nordriman-11-acid methyl ester 

Downstream Products

• 455331-85-8 (+)-zonarol dibenzyl ether 
• 846549-87-9 (+)-11-(2,5-dibenzyloxyphenyl)-8-oxo-12-nordrimane 

Relevant academic research and scientific papers

Total synthesis of two 12-nordrimanes and the pharmacological active sesquiterpene hydroquinone yahazunol

The synthesis of two 12-nordrimanes and yahazunol was achieved via 8-oxo-12-nordrimanic acid methyl ester. The cytotoxic activity of yahazunol and seven other sesquiterpene hydroquinones and sesquiterpene quinones has been determined.