846577-19-3

Upstream product

• 61692-11-3 cis-1,4-Bis(t-Butyldimethylsilyl)cyclopent-2-ene-1,4-diol 
• 846577-22-8 (2R,3S,4R,6S,7R,8S)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-2,8-dimethyl-nonane-1,3,7,9-tetraol 
• 846577-20-6 (2Z,7Z)-(4S,6R)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-2,8-dimethyl-nona-2,7-dienedioic acid dimethyl ester 
• 846577-21-7 (2Z,7Z)-(4S,6R)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-2,8-dimethyl-nona-2,7-diene-1,9-diol 
• 846577-23-9 C₃₉H₆₄O₈Si₂ 

Downstream Products

• 846577-34-2 Methanesulfonic acid (2S,3S)-3-[(1R,2R,3S,5R,6S,7S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-7-((2S,3S)-3-methanesulfonyloxymethyl-oxiranyl)-2,6-bis-(4-methoxy-benzyloxy)-1-methyl-octyl]-oxiranylmethyl ester 
• 846577-27-3 Acetic acid (2E,13E)-(4R,5S,6R,7S,9R,10S,11R,12R)-15-acetoxy-7,9-bis-(tert-butyl-dimethyl-silanyloxy)-4,12-dihydroxy-6,10-bis-(4-methoxy-benzyloxy)-5,11-dimethyl-pentadeca-2,13-dienyl ester 
• 846577-33-1 (2E,11E)-(4R,5S,6R,8S,9R,10S)-6,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,9-bis-(4-methoxy-benzyloxy)-4,10-dimethyl-trideca-2,11-dienedioic acid diethyl ester 
• 846577-25-1 {(2S,3S)-3-[(1R,2R,3S,5R,6S,7S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-7-((2S,3S)-3-hydroxymethyl-oxiranyl)-2,6-bis-(4-methoxy-benzyloxy)-1-methyl-octyl]-oxiranyl}-methanol 
• 860622-32-8 Benzoic acid (2S,3S,4R,5R,6S)-6-[(2R,3S,4S,5S,6S)-6-((R)-1,2-dihydroxy-ethyl)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylsulfanylthiocarboxyoxy-tetrahydro-pyran-2-ylmethyl]-5-(4-methoxy-benzyloxy)-4-methyl-2-vinyl-tetrahydro-pyran-3-yl ester 
• 846577-30-8 benzoic acid 6-[6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylsulfanylthiocarboxyoxy-tetrahydro-pyran-2-ylmethyl]-5-(4-methoxy-benzyloxy)-4-methyl-2-vinyl-tetrahydro-pyran-3-yl ester 
• 846577-24-0 (2E,11E)-(4S,5R,6S,8R,9S,10R)-6,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,9-bis-(4-methoxy-benzyloxy)-4,10-dimethyl-trideca-2,11-diene-1,13-diol 
• 846577-26-2 (3R,4S,5R,6S,8R,9S,10R,11R)-6,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,9-bis-(4-methoxy-benzyloxy)-4,10-dimethyl-trideca-1,12-diene-3,11-diol 
• 846577-29-5 Benzoic acid (2S,3S,4R,5R,6S)-5-(4-methoxy-benzyloxy)-6-[(2R,3S,4S,5S,6S)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylsulfanylthiocarboxyoxy-6-vinyl-tetrahydro-pyran-2-ylmethyl]-4-methyl-2-vinyl-tetrahydro-pyran-3-yl ester 
• 846577-28-4 Benzoic acid (2S,3S,4R,5R,6S)-6-[(2R,3S,4R,5S,6S)-5-hydroxy-3-(4-methoxy-benzyloxy)-4-methyl-6-vinyl-tetrahydro-pyran-2-ylmethyl]-5-(4-methoxy-benzyloxy)-4-methyl-2-vinyl-tetrahydro-pyran-3-yl ester 
• 846577-18-2 Acetic acid (2E,13E)-(4R,5R,6S,7R,9S,10R,11S,12R)-15-acetoxy-4,7,9,12-tetrahydroxy-6,10-bis-(4-methoxy-benzyloxy)-5,11-dimethyl-pentadeca-2,13-dienyl ester 
• 846577-17-1 C₃₃H₄₄O₈ 
• 846577-32-0 (2R,3R,4S,6R,7S,8S)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-3,7-bis-(4-methoxy-benzyloxy)-2,8-dimethyl-nonanedial 

Relevant academic research and scientific papers

Synthetic efforts toward the C22-C36 subunit of halichondrin B utilizing local and imposed symmetry

(Chemical Equation Presented) The C22-C34 portion (2) of halichondrin B was synthesized from meso-symmetric bis-silyl protected cyclopentenediol (7) in 20 steps and 7% overall yield. This was accomplished through a two-directional synthesis/terminus diffe