84691-16-7Relevant academic research and scientific papers
GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
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, (2017/03/17)
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula II.
GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
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, (2017/03/08)
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I), as follows: wherein R1, R2, R4, W, X, Y, and G, are defined herein.
GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
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, (2017/03/08)
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (III); wherein R1c, R2C, R4C, Wc, Yc, Zc and Gc, are defined herein.
HETEROCYCLIC SUBSTITUTED TRIFLUOROMETHYL PYRIMIDINONES AND THEIR USE
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, (2016/10/04)
The present application relates to novel heterocyclically substituted 6-(trifluoromethyl)pyrimidin-4(3H)-one derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular, renal, inflammatory and fibrotic diseases.
HETEROCYCLICALLY SUBSTITUTED TRIFLUOROMETHYLPYRIMIDINONES AND THEIR USE
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, (2017/02/24)
The present application relates to novel heterocyclically substituted 6-(trifluoromethyl)pyrimidin-4(3H)-one derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular, renal, inflammatory and fibrotic diseases.
Anti-ulcer pyridyloxy derivatives, their preparation and uses
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, (2008/06/13)
Compounds of formula (I): STR1 [wherein: R1 is a cyclic amino group, or a dialkylamino group; R2 a group of formula --NHCHR3 R4 wherein R3 and R4 are each alkyl aryl or aralkyl, or together form a cycloalkyl group, or R2 is an aromatic heterocyclic group, or a group of formula --B--S(O)m --R5 wherein R5 is a substituted alkyl group, or an aromatic heterocyclic group; B is an alkylene or alkylidene group; m is 0, 1 or 2; A is a group of formula --CH=CH-- or --(CH2)n --, where n is 1, 2 or 3]; and salts thereof have valuable anti-ulcer activity.
