84697-08-5

Usage

InChI:InChI=1/C10H12O4/c1-13-6-7-14-10(12)8-2-4-9(11)5-3-8/h2-5,11H,6-7H2,1H3

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 99-96-7 4-hydroxy-benzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 

Downstream Products

• 70193-43-0 4-[3-(4-Chloro-phenoxy)-2-oxo-propoxy]-benzoic acid 2-methoxy-ethyl ester 
• 70193-59-8 4-[3-(4-Bromo-phenoxy)-2-oxo-propoxy]-benzoic acid 2-methoxy-ethyl ester 
• 70193-88-3 4-[3-(4-tert-Butyl-phenoxy)-2-oxo-propoxy]-benzoic acid 2-methoxy-ethyl ester 

Relevant academic research and scientific papers

Metallocenes as anti-tumor drugs

The invention relates to novel titanocene derivatives possessing chemotherapeutic activity and method for their preparation. These compounds possess two cyclopentadiene rings linked to titanium as a central atom and bound covalently to two phenoxy groups which possess a substituent R selected from the group consisting of COOCH3, COOC2 H5, H, COOCH2 CH2 OCH2 CH2 OCH3 and are free from amino, nitro, chloride and fluoride groups. The novel compounds represent a compromise between the main properties for an antitumor agent, i.e., electrophilicity and stability, being water soluble. Cytotoxicity measurements of these compounds showed significant growth inhibition properties, expressed in terms of IC50 [M] values.

Synthesis, Characterization, and Thermotropic Properties of Liquid Crystals with an Oligo (Ethylene Oxide) Monomethyl Substituent I: Biphenyl-Based Systems

New alkene liquid crystals 4-[oligo(ethylene oxide)n monomelhylether)carbonyl]phenyl 4-[4(allyloxy)phenyl]benzoate(MBPBEn, n = 1-3), 4′-[oligo(ethylene oxide)n monomethylether)carbonyl]biphenyl4-yl 4-[4-(allyloxy)phenyl]benzoate(MBPBPEn, n = 1-3), (S)-4-[(2-methyl-1-butoxy)carbonyl]phenyl 4-[4-(allyloxy)phenyl]benzoate(MBPBKA), and (S)-4′ -[(2-methyl-1-butoxy)carbonyl]biphenyl-4-yl 4-[4-(allyloxy)phenyl]benzoate(MBPBPKA) were synthesized and characterized using 1H-NMR and elemental analysis methods. The thermal transition temperatures, mesomorphic properties, and mesophase textures of these compounds have been determined by differential scanning calorimetry (DSC), by polarizing optical microscopy, and by X-ray diffraction analysis. The effect of changes in chemical structure on the mesophase properties, mesophase and isotropic transition temperatures, and mesophase textures are discussed.

Sebosuppressive topical cosmetic preparations containing alkoxybenzoic acid esters, process for inhibiting sebum production and alkoxybenzoic acid esters

A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula STR1 wherein R1 represents a C6-20 -n-alkyl and R2 is a member selected from the group consisting of --CH2 OR3, --C2 H4 OR3, --CH2 OC2 H4 OR3, --CH2 OH, --C2 H4 OH, --CH(CH3)OH, --CH2 NR3 R4, --C2 H4 NR3 R4, --CO2 R3 and --CH2 CO2 R3, wherein R3 and R4 are C1-4 -alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application; as well as the process for reducing sebaceous cell sebum production in a mammal in need thereof using the above cosmetic preparation; and the alkoxybenzoic acid esters of the above formula.