847049-75-6

Upstream product

• 847049-69-8 methyl (1R,2S)-2-{(1E,6S)-6-[(4-methoxybenzyl)oxy]hept-1-enyl}cyclopentanecarboxylate 
• 847049-73-4 (1R,2S)-2-{(1E,6S)-6-[(4-methoxybenzyl)oxy]hept-1-enyl}cyclopentanecarbaldehyde 
• 502650-66-0 2-hydroxymethyl-cyclopentanecarboxylic acid methyl ester 
• 847049-72-3 1-methoxy-4-{[(2S)-pent-4-en-2-yloxy]methyl}benzene 
• 824-94-2 p-methoxybenzyl chloride 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 847049-74-5 (4S)-4-hydroxy-4-{(1R,2S)-2-[(1E,6S)-6-[(4-methoxybenzyl)oxy]hept-1-enyl]cyclopentyl}but-2-ynyl acetate 

Downstream Products

• 847049-78-9 (2E,4R)-4-[(tert-butyldiphenylsilyl)oxy]-4-{(1R,2S)-2-[(1E,6S)-6-[(4-methoxybenzyl)oxy]hept-1-enyl]cyclopentyl}but-2-enoic acid 
• 847049-79-0 (2E,4R)-4-[(tert-butyldiphenylsilyl)oxy]-4-{(1R,2S)-2-[(1E,6S)-6-hydroxyhept-1-enyl]cyclopentyl}but-2-enoic acid 
• 847049-80-3 (1R,6S,11aS,14aR)-1-[(tert-butyldiphenylsilyl)oxy]-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one 
• 73899-78-2 (+)-brefeldin C 
• 847049-77-8 (2E,4R)-4-[(tert-butyldiphenylsilyl)oxy]-4-{(1R,2S)-2-[(1E,6S)-6-[(4-methoxybenzyl)oxy]hept-1-enyl]cyclopentyl}but-2-enal 

Relevant academic research and scientific papers

Total synthesis of (+)-brefeldin C, (+)-nor-Me brefeldin A and (+)-4-epi-nor-Me brefeldin A

A total synthesis of (+)-brefeldin C (BFC) and two brefeldin A (BFA) analogues - (+)-nor-Me BFA and (+)-4-epi-nor-Me BFA - has been developed. Key features of the syntheses include desymmetrization of meso anhydrides, a Carreira reaction to control the ab

A new total synthesis of (+)-brefeldin C

A new synthesis of (+)-brefeldin C featuring a Bolm desymmetrisation reaction, a B-alkyl Suzuki-Miyaura cross-coupling and a Carreira alkynylation reaction as the key steps is reported.