84713-75-7Relevant academic research and scientific papers
α-METHYL AMINO ACIDS BY CATALYTIC PHASE-TRANSFER ALKYLATIONS
O'Donnell, Martin J.,LeClef, Brigitte,Rusterholz, David B.,Ghosez, Leon,Antoine, Jean-Pierre,Navarro, Mirtha
, p. 4259 - 4262 (2007/10/02)
The α-methyl amino acids, α-methyl p-chlorophenylalanine, α-methyl p-tyrosine, α-methyl m-tyrosine and α-methyl DOPA have been prepared in good yields from amino ester hydrochlorides.The key step in the method is the catalytic phase-transfer alkylation of Schiff base derivatives of monoalkyl amino acids.
