847139-22-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 5334-39-4 3-methyl-4-nitro-1H-pyrazole 

Downstream Products

• 847139-23-5 tert-butyl 4-amino-3-methyl-1H-pyrazole-1-carboxylate 
• 1630984-98-3 tert-butyl (5S,7S)-7-((tert-butoxycarbonyl)amino)-5-(3-chlorophenyl)-3-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-1-carboxylate 
• 1630984-87-0 tert-butyl (5S,7S)-7-((tert-butoxycarbonyl)amino)-3-methyl-5-(4-nitrophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-1-carboxylate 
• 1630984-96-1 tert-butyl (5R,6R,7S)-7-(((benzyloxy)carbonyl)amino)-5-ethyl-3,6-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-1-carboxylate 
• 1630984-99-4 tert-butyl (5S,7S)-7-(((benzyloxy)carbonyl)amino)-5-(4-bromophenyl)-3-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-1-carboxylate 
• 1630984-91-6 tert-butyl (5S,7S)-7-(((benzyloxy)carbonyl)amino)-3-methyl-5-(2-methylprop-1-en-1-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-1-carboxylate 

Relevant academic research and scientific papers

VEGFR3 INHIBITORS

This invention relates to a compound of the formula (I): The invention also relates to processes for the preparation of the compound of the formula (I), pharmaceutical agents or compositions containing the compound or a method of using the compound for th

Chiral phosphoric acid-catalyzed enantioselective three- component aza-diels-alder reactions of aminopyrroles and aminopyrazoles

A highly stereoselective three-component Povarov reaction, catalyzed by (R)- and (S)-BINOL hydrogen phosphate, was achieved for the first time with aminopyrroles and aminopyrazoles as 2-azadiene precursors. A variety of aldehydes, enecarbamates, amino-substituted azines participated in the reaction to afford the tetrahydropyrrolopyridines and tetrahydropyrazolopyridines in good yields with excellent diatereo- and enantioselectivities. A stereochemical model is proposed to account for the observed absolute stereochemistry.

PYRIDINE COMPOUNDS

The present invention relates to compounds that inhibit of focal adhesion kinase function, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment in warm-blooded animals such as humans of diseases such as cancer.