847199-25-1Relevant academic research and scientific papers
Vanadium-catalyzed asymmetric oxidation of α-hydroxy esters using molecular oxygen as stoichiometric oxidant
Radosevich, Alexander T.,Musich, Christine,Toste, F. Dean
, p. 1090 - 1091 (2005)
A vanadium-catalyzed method for the oxidative kinetic resolution of α-hydroxyesters, using oxygen as the terminal oxidant, is described. The catalyst is generated in situ from vanadium(V) tri-iso-propoxyoxide in combination with a tridentate ligand derived from 3,5-di-tert-butylsalicylaldehyde and (S)-tert-leucinol. The reaction allows for the enantioselective synthesis of both aromatic and aliphatic secondary alcohols, including those containing olefins and alkynes. Copyright
