847259-16-9Relevant academic research and scientific papers
Diels-alder reactions with cyclic sulfones: VII. Synthesis of 1-benzothiophene 1,1-dioxide derivatives
Andreev,Shul'ts,Volkov,Shakirov,Bagryanskaya,Gatilov,Tolstikov
, p. 854 - 865 (2004)
5-Arylmethylene-2,2-dimethyl-1,3-dioxane-4,6-diones reacted with 5-isopropenyl-2,3-dihydrothio-phene 1,1-dioxide to give the corresponding ortho-addition products, 5-aryl-2',2',7-trimethyl-3,3a,5,6-tetra-hydro-2H- spiro[1-benzothiophene-4,5'-[1,3]dioxane]-4',6'-dione 1,1-dioxides. Their aminolysis resulted in opening of the 1,3-dioxane ring and formation of 4-carbamoyl-7-methyl-2,3,3a,4,5,6-hexahydro-1-benzo-thiophene-4-carboxylic acid 1,1-dioxide whose structure was determined by X-ray analysis. Reactions of the spiro adducts with amines and hydrazine hydrate afforded the corresponding mono- or dicarboxylic acid monoamides (hydrazide).
Modular synthesis of tetrahydrofluorenones from 5-alkylidene Meldrum's acids
Fillion, Eric,Dumas, Aaron M.,Hogg, Sylvia A.
, p. 9899 - 9902 (2007/10/03)
The one-pot synthesis of tetrahydrofluorenones, the core 6-5-6 tricyclic structural motif found in norditerpenoid natural products, from alkylidene Meldrum's acids via thermal Diels-Alder/BF3·OEt 2-catalyzed Friedel-Crafts acylation
