847489-05-8Relevant academic research and scientific papers
Design at the atomic level: Design of biaryloxazolidinones as potent orally active antibiotics
Zhou, Jiacheng,Bhattacharjee, Ashoke,Chen, Shili,Chen, Yi,Duffy, Erin,Farmer, Jay,Goldberg, Joel,Hanselmann, Roger,Ippolito, Joseph A.,Lou, Rongliang,Orbin, Alia,Oyelere, Ayomi,Salvino, Joe,Springer, Dane,Tran, Jennifer,Wang, Deping,Wu, Yusheng,Johnson, Graham
scheme or table, p. 6175 - 6178 (2009/06/30)
We have developed a first generation of hybrid sparsomycin-linezolid compounds into a new family of orally bioavailable biaryloxazolidinones that have activity against both linezolid-susceptible and -resistant Gram-positive bacteria as well as the fastidi
