847495-07-2

Upstream product

• 142663-85-2 3-amino-(2S)-[(1,1-dimethylethoxycarbonyl)amino]-propionic acid benzyl ester 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 847494-17-1 (2S)-[(1,1-dimethylethoxycarbonyl)amino]-3-(3-phenylureido)propionic acid 

Relevant academic research and scientific papers

Proteasome inhibitors and methods of using the same

The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly or indirectly with proteasome activity.

PROTEASOME INHIBITORS AND METHODS OF USING THE SAME

The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.