84751-66-6Relevant academic research and scientific papers
Free Radical Ring Expansion of Fused-Methylenecyclobutanes
Zhang, Wei,Dowd, Paul
, p. 8539 - 8542 (2007/10/02)
Fused methylenecyclobutanes comprise a new free radical ring expansion system leading to cis-fused methylenecycloheptanes.
Free-Radical Ring Expansion of Fused Cyclobutanones: Stereospecific Construction of 5,7-, 6,7-, 7,7-, 8,7-, and 5,8-Cis-Fused Bicyclic Systems
Dowd, Paul,Zhang, Wei
, p. 7163 - 7171 (2007/10/02)
A new method of appending seven- and eight-membered rings to cycloalkenes is described.Treatment of selected alkene precursors with an ω-bromoalkyl ketene or a keteniminium salt leads to haloalkyl cyclobutanone formation.Tri-n-butyltin hydride promoted ring expansion then yields the annulated product.Since the initial cyclobutanone is cis fused, the final product is also produced stereospecifically with a cis ring fusion.
A Novel Method of Annulation through α,β-Epoxy Sulfoxides with the Aid of Intramolecular Radical Cyclization
Satoh, Tsuyoshi,Itoh, Masayuki,Yamakawa, Koji
, p. 1949 - 1950 (2007/10/02)
A novel method of annulation was realized from ketones through α,β-epoxy sulfoxides with the aid of endo-type intramolecular radical cyclization.In these reactions 1-chloroalkyl phenyl sulfoxides having phenylseleno group on an end of the alkyl group acted as synthons of the annulation.
