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Z-Aib-Gly-OtBu is a tripeptide, a chain of three amino acids, consisting of Z-Aib (N-benzyloxycarbonyl-α-aminoisobutyric acid), Gly (glycine), and OtBu (tert-butyloxycarbonyl). The Z-Aib is a non-natural amino acid with a bulky side chain, which can influence the conformation and stability of the peptide. Glycine is the simplest amino acid, and its presence often allows for greater flexibility in the peptide chain. The OtBu group is a protecting group used in peptide synthesis to prevent unwanted side reactions, particularly during the coupling of amino acids. This specific sequence is of interest in the field of peptide chemistry, where it can be used to study the effects of non-natural amino acids on peptide structure and function, as well as in the development of new drugs and bioactive molecules.

84758-68-9

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84758-68-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84758-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,7,5 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84758-68:
(7*8)+(6*4)+(5*7)+(4*5)+(3*8)+(2*6)+(1*8)=179
179 % 10 = 9
So 84758-68-9 is a valid CAS Registry Number.

84758-68-9Downstream Products

84758-68-9Relevant academic research and scientific papers

SYNTHESE VON 2-METHYLALANIN-PEPTIDEN, DIE pH-ABHAENGIGKEIT IHRER 13C-NMR-SPECTREN UND EINE NEUE METHODE ZUR AUSWERTUNG UEBER CS-DIAGRAMME

Leibfritz, Dieter,Haupt, Erhard,Dubischar, Norbert,Lachmann, Heinrich,Oekonomopulos, Raymond,Jung, Guenther

, p. 2165 - 2182 (2007/10/02)

The uncommon amino-acid 2-methylalanine (α-aminoisobutiryc acid, Aib) was investigated by 13C-NMR.The chemical shifts of amino- or carboxy-protected derivates of Aib and of protected oligopeptides are discussed with respect to neighbouring groups and amino acids.The pH-dependence of the 13C-NMR spectra of Aib, Aib-Ala, Ala-Aib, Aib-Ala-Aib and Aib-Ala-Aib-Ala-Aib was studied.Using these examples, a new and advantageous method is demonstrated for the first time for the evaluation of NMR titration curves, which uses so-called chemical shift diagrams (CS diagrams).

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