84758-81-6

Basic information

• Product Name: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride
• Synonyms: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride;2-Amino-2-methylpropionic acid tert-butyl ester hydrochloride;tert-Butyl 2-amino-2-methylpropanoate hydrochloride;EOS-62338
• CAS NO: 84758-81-6
• Molecular Formula: C₈H₁₇NO₂*ClH
• Molecular Weight: 195.68702
• Mol File: 84758-81-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Soluble in water or 1% acetic acid.
• CAS DataBase Reference: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(84758-81-6)
• EPA Substance Registry System: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(84758-81-6)

Safety Data

• Hazardous Substances Data: 84758-81-6(Hazardous Substances Data)

Usage

Uses

tert-Butyl 2-aminoisobutyrate hydrochloride is used as intermediates.

Upstream product

• 4512-31-6 benzyloxycarbonyl-α-aminoisobutyric acid tert-butyl ester 

Downstream Products

• 1006899-17-7 tert-butyl 2-methyl-2-[3-(4-methylsulfanyl-3-trifluoromethylphenyl)ureido]propionate 
• 1434643-13-6 diethyl 5-{[(2-tert-butoxy-1,1-dimethyl-2-oxoethyl)carbamoyl] amino}-3-methylthiophene-2,4-dicarboxylate 
• 1192477-70-5 C₂₆H₃₆N₂O₅ 
• 1090903-32-4 2-(2-amino-phenylamino)-2-methyl-propionic acid tert-butyl ester 
• 1432584-87-6 (Z)-N-(2-(((benzyloxy)carbonyl)amino)-2-methylpropylidene)-1-(tert-butoxy)-2-methyl-1-oxopropan-2-amine oxide 
• 1432584-86-5 (S,Z)-N-((1-((benzyloxy)carbonyl)pyrrolidin-2-yl)methylene)-1-(tert-butoxy)-2-methyl-1-oxopropan-2-amine oxide 
• 83537-94-4 Benzyloxycarbonyl-α-aminoisobutyryl-α-aminoisobutyric acid tert butyl ester 

Relevant articles and documents

SYNTHESE VON 2-METHYLALANIN-PEPTIDEN, DIE pH-ABHAENGIGKEIT IHRER 13C-NMR-SPECTREN UND EINE NEUE METHODE ZUR AUSWERTUNG UEBER CS-DIAGRAMME

The uncommon amino-acid 2-methylalanine (α-aminoisobutiryc acid, Aib) was investigated by 13C-NMR.The chemical shifts of amino- or carboxy-protected derivates of Aib and of protected oligopeptides are discussed with respect to neighbouring groups and amino acids.The pH-dependence of the 13C-NMR spectra of Aib, Aib-Ala, Ala-Aib, Aib-Ala-Aib and Aib-Ala-Aib-Ala-Aib was studied.Using these examples, a new and advantageous method is demonstrated for the first time for the evaluation of NMR titration curves, which uses so-called chemical shift diagrams (CS diagrams).