847591-25-7Relevant academic research and scientific papers
Domino functionalizations of the amino terminus of 6-aminopenicillanates with Ph3PCCO
Schobert, Rainer,Stangl, Andreas
, p. 1127 - 1130 (2005)
6-Aminopenicillanates, or the sulfoxides or the sulfones thereof, were N-acylated in a three-component reaction with an aldehyde and Ph3PCCO to give the corresponding 6-(E-2′-alkenoyl)amides. This domino addition-Wittig alkenation sequence was extended by an additional Claisen rearrangement step in the side-chain in the case of 5g.
