847666-80-2Relevant academic research and scientific papers
N-Methyl substituted 2′,4′-BNANC: A highly nuclease-resistant nucleic acid analogue with high-affinity RNA selective hybridization
Miyashita, Kazuyuki,Rahman, S. M. Abdur,Seki, Sayori,Obika, Satoshi,Imanishi, Takeshi
, p. 3765 - 3767 (2007)
Oligonucleotides modified with a novel BNA analogue, 2′, 4′-BNANC[N-Me], were synthesized, and in comparison to 2′,4′-BNA (LNA), have similarly high RNA affinity, better RNA selectivity and much higher resistance to nuclease degradation, sugges
NOVEL ARTIFICIAL NUCLEIC ACIDS OF N-O BOND CROSSLINKAGE TYPE
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Page/Page column 16; 20, (2010/11/08)
It is intended to provide oligonucleotide analogs usable in, for exmaple, the antisense method which are highly tolerant to enzymes, have a strong and selective binding affinity for a single-stranded RNA and also are highly capable of forming a triple-str
