847685-02-3

Upstream product

• 225385-91-1 (3,4-difluoro-phenyl)-carbamic acid methyl ester 
• 79-22-1 methyl chloroformate 
• 847685-01-2 2-iodo-4,5-difluoroaniline 

Downstream Products

• 847685-05-6 1-(4-tert-butyl-benzyl)-3-(5,6-difluoro-benzo[b]thiophen-3-yl)-4-(5,6-difluoro-1H-indol-3-yl)-pyrrole-2,5-dione 
• 847685-04-5 3-bromo-1-(4-tert-butyl-benzyl)-4-(5,6-difluoro-1H-indol-3-yl)-pyrrole-2,5-dione 
• 169674-01-5 5,6-difluoro-1H-indole 
• 847685-03-4 (4,5-difluoro-2-trimethylsilanylethynyl-phenyl)-carbamic acid methyl ester 

Relevant academic research and scientific papers

Process for the preparation of an indole derivative

A process for the preparation of indole derivatives of formula (I): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.

Highly convergent synthesis of a rebeccamycin analog with benzothioeno(2,3-a)pyrrolo(3,4-c)carbazole as the aglycone

A highly convergent, scalable synthesis of the rebeccamycin analog 2 was demonstrated in seven steps and 31% overall yield based on the N-protected building block dibromomaleimide 7. The practical synthesis of other two building blocks, 5,6-difluoro-3-ben